- Pregnant women and their developing fetuses;
- Women who are planning to become pregnant;
- Nursing women and their newborns and infants;
- Children, especially those younger than 6 years of age;
- People with preexisting neurological disease such as multiple sclerosis, Alzheimer’s disease or Parkinson’s disease
- People with impaired kidney function; and
- People with known heightened sensitivity (allergy) to mercury or other components of dental amalgam.
Dental amalgam is a mixture of mercury and a powdered alloy made up of silver, tin and copper, the release said. Over time, the amalgam releases small amounts of mercury vapor. Certain behaviors such as teeth grinding impact how much vapor is released over time.
“These uncertainties in the most vulnerable patients are why today we are recommending people who may be at high risk for adverse health effects of mercury exposure use non-mercury alternatives to dental amalgam, such as composite resins and glass ionomer cement fillings,” Dr. Jeffrey Shuren, director of FDA’s Center for Devices and Radiological Health, said in a news release. “Dental amalgam-related mercury vapor release may be highest during placement or removal of the filling.”